Nature Reviews Molecular Cell Biology

Ageing, repetitive genomes and DNA damage

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Abstract

The mitochondrial production of reactive oxygen species is inversely proportional to longevity in animals. A key question now is, which molecules, among those that are oxidized, affect the lifespan of the organism most significantly?

The paper

USC Norris Comprehensive Cancer Center; University of Southern California

Nature Reviews Molecular Cell Biology, 1 Jan 2004

doi.org/10.1038/nrm1281PubMed 14708011