MechanismsAnimals
Metabolic and Microbial Mastery: Unveiling the Secrets of Naked Mole-Rat Longevity
GSA 2025 Abstract
Abstract
Naked mole-rats (Heterocephalus glaber) stand out among mammals for their extraordinary longevity, showing no increase in mortality risk with age and maintaining robust physiological and molecular stability throughout their 40-year lifespan.
- Lipid and ceramide metabolism
- Methionine and one-carbon metabolism
- Microbiome composition
- Alpha-tocopherol
- Glutathione
- Mice
