FECAL TRANSPLANT FROM LONG LIVING AMES DWARF MICE ALTERS THE MICROBIOME AND BIOMARKERS OF LIVER HEALTH IN CONTROL MICE

Abstract

Aging is associated with intestinal dysbiosis, a condition characterized by diminished microbial biodiversity and inflammation. This leads to increased vulnerability to extraintestinal manifestations such as autoimmune, metabolic, and neurodegenerative conditions and accelerates mortality.