Caenorhabditis species

1. Phenformin extends lifespan in C. species.

   “phenformin prompts robust lifespan extension in the face of environmental changes”

   Model organismsenvironmental changes and genetically diverse Caenorhabditis species

   Environmental factors capable of broadly interfering with nutritional lifespan extension paradigms

   iScience·6 Jun 2025

More on Phenformin

1. Glucose, dipeptides, and trace elements inhibit metformin-mediated lifespan extension in C. species.

   “we traced the ability of certain agars to interfere with metformin-prompted lifespan extension to differences in glucose, dipeptide, and trace element levels.”

   Model organismsdifferences in agar composition during metformin treatment

   Environmental factors capable of broadly interfering with nutritional lifespan extension paradigms

   iScience·6 Jun 2025

More on Glucose, dipeptides, and trace elements

1. Agar is associated with metformin-mediated lifespan extension in C. species.

   “variation in agar from lot-to-lot or from different manufacturers influences metformin's ability to extend lifespan in diverse Caenorhabditis species.”

   Model organismsmetformin treatmentdifferent lots or manufacturers

   Environmental factors capable of broadly interfering with nutritional lifespan extension paradigms

   iScience·6 Jun 2025

More on Agar