AgingResearch.NewsJoin free

Glucose, dipeptides, and trace elements

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Boston Area Diabetes Endocrinology Research Center and 6 more
  • Model organisms1

Outcomes

1

Metformin-mediated lifespan extension

downin C. species1

1 study

  1. Glucose, dipeptides, and trace elements inhibit metformin-mediated lifespan extension in C. species.

    “we traced the ability of certain agars to interfere with metformin-prompted lifespan extension to differences in glucose, dipeptide, and trace element levels.”

    Model organismsdifferences in agar composition during metformin treatment

    Environmental factors capable of broadly interfering with nutritional lifespan extension paradigms

    iScience6 Jun 2025

Latest

Related