Young regulatory t cell-derived extracellular vesicles

Intervention

1 paper4 findings

  • 1 lab in 1 country
  • Funder: National Natural Science Foundation of China
  • Animals1

Outcomes

4

Cellular senescence

downin mouse cells1

1 study
  1. Young regulatory t cell-derived extracellular vesicles decrease cellular senescence in mouse cells.

    “attenuated cellular senescence, reduced reactive oxygen species (ROS) accumulation, and enhanced mitochondrial respiration”

    Cellssenescent cell models

    Young Regulatory T Cell-Derived Extracellular Vesicles Improve Mitochondrial Function and Angiogenesis and Suppress Inflammation in Senescent Brain and Heart

    Journal of neurochemistry1 Mar 2026

More on Cellular senescence

Inflammation

downin mice1

1 study
  1. Young regulatory t cell-derived extracellular vesicles decrease inflammation in mice.

    “attenuated inflammatory responses”

    Animalsmales

    Young Regulatory T Cell-Derived Extracellular Vesicles Improve Mitochondrial Function and Angiogenesis and Suppress Inflammation in Senescent Brain and Heart

    Journal of neurochemistry1 Mar 2026

More on Inflammation

Mitochondrial biogenesis (PGC-1α)

upin mice1

1 study
  1. Young regulatory t cell-derived extracellular vesicles increase mitochondrial biogenesis (PGC-1α) in mice.

    “promoted mitochondrial biogenesis, facilitated vascular repair and regeneration, as well as attenuated inflammatory responses”

    Animalsmales

    Young Regulatory T Cell-Derived Extracellular Vesicles Improve Mitochondrial Function and Angiogenesis and Suppress Inflammation in Senescent Brain and Heart

    Journal of neurochemistry1 Mar 2026

More on Mitochondrial biogenesis (PGC-1α)

Lifespan

upin mice1

1 study
  1. Young regulatory t cell-derived extracellular vesicles extend lifespan in mice.

    “ultimately prolonged the survival of aged male C57BL/6 mice”

    Animalsmales

    Young Regulatory T Cell-Derived Extracellular Vesicles Improve Mitochondrial Function and Angiogenesis and Suppress Inflammation in Senescent Brain and Heart

    Journal of neurochemistry1 Mar 2026

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