Vitamin B12-LOADED chitosan nanoparticles

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Animals1

Outcomes

Satellite cell differentiation

upin rats1

1 study

Vitamin B12-LOADED chitosan nanoparticles increase satellite cell differentiation in rats.
“Supplementation with B12 CS NPS significantly enhanced satellite cell proliferation and differentiation”
Animalsafter doxorubicin-induced acute myotoxicitygastrocnemius muscle
Vitamin B12-Loaded Chitosan Nanoparticles Promote Skeletal Muscle Injury Repair in Aged Rats via Amelioration of Aging-Suppressed Efferocytosis
Biomolecules7 Dec 2025

Satellite cell proliferation

upin rats1

1 study

Vitamin B12-LOADED chitosan nanoparticles increase satellite cell proliferation in rats.
“Supplementation with B12 CS NPS significantly enhanced satellite cell proliferation and differentiation”
Animalsafter doxorubicin-induced acute myotoxicitygastrocnemius muscle
Vitamin B12-Loaded Chitosan Nanoparticles Promote Skeletal Muscle Injury Repair in Aged Rats via Amelioration of Aging-Suppressed Efferocytosis
Biomolecules7 Dec 2025

Necrotic tissue areas

downin rats1

1 study

Vitamin B12-LOADED chitosan nanoparticles decrease necrotic tissue areas in rats.
“B12 CS NPS administration significantly improved efferocytosis and reduced necrotic tissue areas”
Animalsafter doxorubicin-induced acute myotoxicitygastrocnemius muscle
Vitamin B12-Loaded Chitosan Nanoparticles Promote Skeletal Muscle Injury Repair in Aged Rats via Amelioration of Aging-Suppressed Efferocytosis
Biomolecules7 Dec 2025

efferocytosis

upin rats1

1 study

Vitamin B12-LOADED chitosan nanoparticles improve efferocytosis in rats.
“B12 CS NPS administration significantly improved efferocytosis and reduced necrotic tissue areas”
Animalsafter doxorubicin-induced acute myotoxicitygastrocnemius muscle
Vitamin B12-Loaded Chitosan Nanoparticles Promote Skeletal Muscle Injury Repair in Aged Rats via Amelioration of Aging-Suppressed Efferocytosis
Biomolecules7 Dec 2025

Latest

1 in 12 months

Biomolecules30 Dec