Umbilical cord plasma

Intervention

1 paper5 findings

  • 1 lab in 1 country
  • Funder: National Institute on Aging
  • 5 of 5 findings with company ties
  • Human trial1

Outcomes

5

Mitochondrial DNA copy number

no changein humans1

1 study
  1. Umbilical cord plasma has no effect on mitochondrial DNA copy number in humans.

    “telomere length and mtDNA-CN were not significantly affected by the treatment.”

    Human trialconcentrate1 ml10-weekn = 18

    Umbilical cord plasma concentrate has beneficial effects on DNA methylation GrimAge and human clinical biomarkers

    Aging cell2 Sep 2022

More on Mitochondrial DNA copy number

Telomere length

no changein humans1

1 study
  1. Umbilical cord plasma has no effect on telomere length in humans.

    “while telomere length and mtDNA-CN were not significantly affected by the treatment.”

    Human trialconcentrate1 ml10-weekn = 18

    Umbilical cord plasma concentrate has beneficial effects on DNA methylation GrimAge and human clinical biomarkers

    Aging cell2 Sep 2022

More on Telomere length

eGFR

upin humans1

1 study
  1. Umbilical cord plasma increases eGFR in humans (p = 0.0044).

    “while estimated glomerular filtration rate (eGFR) was increased (p = 0.0044), indicating the treatment may improve biomarkers of kidney function.”

    Human trialconcentrate1 ml10-weekn = 18

    Umbilical cord plasma concentrate has beneficial effects on DNA methylation GrimAge and human clinical biomarkers

    Aging cell2 Sep 2022

More on eGFR

Creatinine

downin humans1

1 study
  1. Umbilical cord plasma decreases creatinine in humans (p = 0.0039).

    “For example, creatinine was significantly decreased (p = 0.0039), while estimated glomerular filtration rate (eGFR) was increased (p = 0.0044)”

    Human trialconcentrate1 ml10-weekn = 18

    Umbilical cord plasma concentrate has beneficial effects on DNA methylation GrimAge and human clinical biomarkers

    Aging cell2 Sep 2022

More on Creatinine

GrimAge

downin humans1

1 study
  1. Umbilical cord plasma decreases GrimAge in humans (-0.82 years, p = 0.0093).

    “The treatment reduced DNA methylation-based GrimAge by an average of 0.82 years (p = 0.0093), suggests a reduction in morbidity and mortality risk.”

    Human trialconcentrate1 ml10-weekn = 18

    Umbilical cord plasma concentrate has beneficial effects on DNA methylation GrimAge and human clinical biomarkers

    Aging cell2 Sep 2022

More on GrimAge

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