Ultraviolet radiation

Intervention2 findings

Outcomes

2

CPD hyperhotspot mutations in gene promoters

upin human cells1Low certainty

1 study

  1. Ultraviolet radiation increases CPD hyperhotspot mutations in gene promoters in human cells (1000-fold higher frequencies).

    Cellsdays

    UV signature mutation hyperhotspots as genomic dosimeters · Photochemistry and photobiology · 22 Sep 2026

CPD hyperhotspot mutations in gene promoters →

Mutations at skin cancer tumor suppressor gene hotspot nt

upin human cells1Low certainty

1 study

  1. Ultraviolet radiation induces mutations at skin cancer tumor suppressor gene hotspot nt in human cells.

    Cellslow-dose UVB exposureskinweeks

    UV signature mutation hyperhotspots as genomic dosimeters · Photochemistry and photobiology · 22 Sep 2026

Mutations at skin cancer tumor suppressor gene hotspot nt →

Related