Trichinella spiralis

3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: Instytut Biologii Doswiadczalnej im. M. Nenckiego PAN and 1 more

Outcomes

P16 INK4a

upin mice1

1 study

Trichinella spiralis increases P16 INK4a in mice.
“only p16 INK4a was upregulated on the protein level during the NC development at 26-day old infection, as well as in the mature NC at 7-month old infection.”
Animalsduring NC development at 26-day and mature NC at 7-month old infectionmuscle
Mammalian senescent nurse cell provides Trichinella spp. muscle larvae with cell growth inhibitory capacity
Gene2 Feb 2026

Trichinella spiralis

Outcomes

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