Teicoplanin

1. Teicoplanin has no effect on inflammation in human cells.

   “secretion of IL-1β, IL-6, and MMP-3 remained unchanged in IL-1β-stimulated chondrocytes following teicoplanin exposure”

   Cellsin IL-1β-stimulated chondrocytes

   Dose-dependent cytotoxicity and modulation of catabolic cytokine expression by teicoplanin in human articular chondrocytes

   Toxicology in vitro : an international journal published in association with BIBRA·24 Jul 2026

More on Inflammation

1. Teicoplanin induces cellular senescence in human cells.

   “Cellular senescence was observed following combined IL-1β and teicoplanin treatment”

   Cellsin combination with IL-1β

   Dose-dependent cytotoxicity and modulation of catabolic cytokine expression by teicoplanin in human articular chondrocytes

   Toxicology in vitro : an international journal published in association with BIBRA·24 Jul 2026

More on Cellular senescence

1. Teicoplanin decreases cell viability in human cells.

   “exposure to 100 μg/mL significantly reduced cell viability and proliferation in normal chondrocytes”

   Cellsnormal human articular chondrocytes100 μg/mL

   Dose-dependent cytotoxicity and modulation of catabolic cytokine expression by teicoplanin in human articular chondrocytes

   Toxicology in vitro : an international journal published in association with BIBRA·24 Jul 2026

More on Cell viability

1. Teicoplanin increases chondrotoxicity in human cells.

   “High concentrations of teicoplanin (≥ 200 μg/mL) induced marked chondrotoxicity”

   Cellsnormal human articular chondrocytes≥ 200 μg/mL

   Dose-dependent cytotoxicity and modulation of catabolic cytokine expression by teicoplanin in human articular chondrocytes

   Toxicology in vitro : an international journal published in association with BIBRA·24 Jul 2026