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STOCK1N-57534

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Biotechnology and Biological Sciences Research Council and 5 more

Outcomes

2

Cellular senescence(-like) phenotypes

downin human cells1

1 study

  1. STOCK1N-57534 decreases cellular senescence(-like) phenotypes in human cells.

    “Treatment with STOCK1N-57534 reactivates mitophagy downregulated in senescent and naturally aged donor-derived primary cells, improving cellular senescence(-like) phenotypes.”

    Cellssenescent and naturally aged donor-derived primary cellsprimary human cell

    Mitophagy as a guardian against cellular aging

    Autophagy14 Oct 2024

Mitophagy

upin human cells1

1 study

  1. STOCK1N-57534 activates mitophagy in human cells.

    “Treatment with STOCK1N-57534 reactivates mitophagy downregulated in senescent and naturally aged donor-derived primary cells”

    Cellssenescent and naturally aged donor-derived primary cellsprimary human cell

    Mitophagy as a guardian against cellular aging

    Autophagy14 Oct 2024

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