Sterile inflammation induction
1 paper1 finding
- 1 lab in 1 country
- Funders: Deutsche Forschungsgemeinschaft and 2 more
- Animals1
Outcomes
1Hematopoietic stem cell mutation rate
upin mice1
1 study
Hematopoietic stem cell mutation rate
upin mice1
Sterile inflammation induction increases hematopoietic stem cell mutation rate in mice.
“breaking HSC dormancy via induction of sterile inflammation led to a dramatic acceleration in mutation rate”
Animalsbreaking hematopoietic stem cell dormancyhematopoietic stem cell
Dormancy, not apoptosis, restricts hematopoietic stem cell mutagenesis during aging
bioRxiv (Cold Spring Harbor Laboratory)13 May 2026Preprint
Latest
1 in 12 monthsbioRxiv
Dormancy, not apoptosis, restricts hematopoietic stem cell mutagenesis during aging
Preprint: experiments in miceApoptosis