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SLC12A8 overexpression

InterventionPreclinical

1 paper studies it2 findings

Across all fields, 1 paper: none in people yet, 1 in animals

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 2 countries
  • Funders: Japan Agency for Medical Research and Development and 4 more
  • Animals1

Outcomes

2

Energy expenditure

upin mice1

1 study

  1. SLC12A8 overexpression improves energy expenditure in mice.

    “LH-specific overexpression of Slc12a8 in aged mice significantly ameliorates age-associated decreases in energy expenditure and skeletal muscle functions.”

    Animalslateral hypothalamus

    Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging

    Cell reports

Physical function

upin mice1

1 study

  1. SLC12A8 overexpression improves physical function in mice.

    “LH-specific overexpression of Slc12a8 in aged mice significantly ameliorates age-associated decreases in energy expenditure and skeletal muscle functions.”

    Animalslateral hypothalamus

    Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging

    Cell reports

Latest

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