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Skeletal muscle-derived small extracellular vesicles

Skeletal muscle-derived small extracellular vesicles has been studied in 1 paper since 2026: none in people yet, 1 in animals; 1 in the past year. The research so far is in animals. The newest story, Nov 9, 2026: “Particles from exercised muscle reduced heart injury in mice”.

Intervention

1 paper studies it3 findingsUpdated

1 new paper in 30 daysSee all 1 papers on skeletal muscle-derived small extracellular vesicles

At a glance

The findings reach mice, none yet in people. 1 lab in 1 country.

None of its findings points the other way.

Mice: a single group. Cells, worms or flies and humans: nothing yet.

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

What did studies of skeletal muscle-derived small extracellular vesicles find?

3

Studies of skeletal muscle-derived small extracellular vesicles measured 3 outcomes: mitochondrial respiration, cardiomyocyte apoptosis and myocardial ischemia/reperfusion injury.

Mitochondrial respiration

upin mice1

1 study

  1. Skeletal muscle-derived small extracellular vesicles improve mitochondrial respiration in mice (myocardial ischemia/reperfusion injury).

    “Skeletal muscle-derived sEVs from exercised mice significantly attenuated MI/R injury by reducing cardiomyocyte apoptosis and improving mitochondrial respiration.”

    Animalsmyocardial ischemia/reperfusion injuryderived from exercised skeletal musclecardiomyocyte

    Particles from exercised muscle reduced heart injury in mice

    Circulation research

cardiomyocyte apoptosis

downin mice1

1 study

  1. Skeletal muscle-derived small extracellular vesicles decrease cardiomyocyte apoptosis in mice (myocardial ischemia/reperfusion injury).

    “Skeletal muscle-derived sEVs from exercised mice significantly attenuated MI/R injury by reducing cardiomyocyte apoptosis and improving mitochondrial respiration.”

    Animalsmyocardial ischemia/reperfusion injuryderived from exercised skeletal musclecardiomyocyte

    Particles from exercised muscle reduced heart injury in mice

    Circulation research

Myocardial ischemia/reperfusion injury

downin mice1

1 study

  1. Skeletal muscle-derived small extracellular vesicles decrease myocardial ischemia/reperfusion injury in mice (myocardial ischemia/reperfusion injury).

    “Skeletal muscle-derived sEVs from exercised mice significantly attenuated MI/R injury by reducing cardiomyocyte apoptosis and improving mitochondrial respiration.”

    Animalsmyocardial ischemia/reperfusion injuryderived from exercised skeletal muscleheart

    Particles from exercised muscle reduced heart injury in mice

    Circulation research

More on Myocardial ischemia/reperfusion injury

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 0Nov 2026: 11 paper in 12 months
Circulation Research

Particles from exercised muscle reduced heart injury in mice

Mouse experiments tracked tiny packages released by skeletal muscle after four weeks of exercise and tested their role in limiting heart damage.Mouse experiments tracked tiny packages released by skeletal muscle after four weeks of exercise and tested their role in limiting heart damage.

Mouse studyExercise
Paper

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