SEX-1 knockdown
Intervention1 paper2 findings
- Model organisms1
Outcomes
2Thermosensory function
downin worms1
1 study
Thermosensory function
downin worms1
SEX-1 knockdown impairs thermosensory function in worms.
Model organismsloss of functionamphid neuron
A PPAR-gamma counterpart protects worm neurons by coordinating lipids and mitochondria · bioRxiv · 29 Sep 2026 · Preprint
Mitochondrial dysfunction
upin worms1
1 study
Mitochondrial dysfunction
upin worms1
SEX-1 knockdown induces mitochondrial dysfunction in worms.
Model organismsloss of function
A PPAR-gamma counterpart protects worm neurons by coordinating lipids and mitochondria · bioRxiv · 29 Sep 2026 · Preprint
Latest
1A PPAR-gamma counterpart protects worm neurons by coordinating lipids and mitochondria
Researchers show that SEX-1 regulates sphingolipid metabolism and mitochondrial quality control in Caenorhabditis elegans, but its protective activity declines with age.
bioRxiv · Tsagkari D et al.