Serial transplantation

Serial transplantation decreases marrow stem cell proliferative capacity (Exhaustion after three to six serial transplantations).

“Functional tests generally show that marrow stem cell lines are exhausted after three to six serial transplantations into successive recipients;”

Reviewserial transplantation into successive recipientsbone marrowthree to six serial transplantations

Proliferative capacity of erythropoietic stem cell lines and aging: an overview

Mechanisms of ageing and development·1 Mar 1979