Ipsc-derived hematopoietic stem cells

1. Ipsc-derived hematopoietic stem cells increase telomere length in human cells.

   “single-cell telomere analysis demonstrated restoration of telomere length in iHSCs compared to primary adult HSCs.”

   Cellscompared to primary adult HSCshematopoietic stem cell

   Sustained epigenetic rejuvenation of serially engrafting human iPSC-derived HSCs

   bioRxiv (Cold Spring Harbor Laboratory)·17 Jul 2026Preprint

More on Telomere length

1. Ipsc-derived hematopoietic stem cells decrease epigenetic age in human cells (Reset to near zero in iPSCs; remained under seven years across differentiation and transplantation).

   “epigenetic age was reset to near zero in iPSCs and remained under seven years across differentiation and transplantation.”

   Cellsacross differentiation and transplantation; independent of donor ageinduced pluripotent stem cells and derived hematopoietic stem cells

   Sustained epigenetic rejuvenation of serially engrafting human iPSC-derived HSCs

   bioRxiv (Cold Spring Harbor Laboratory)·17 Jul 2026Preprint

More on Epigenetic age