Selexipag

1. Selexipag inhibits cellular senescence in rats.

   “In vivo and in vitro validation experiments demonstrated that the two candidate agents could suppress NF-κB pathway activation, inflammatory cytokine release, and cellular senescence.”

   Animalsin DKD models

   Aging-driven transcriptional programs in diabetic kidney disease: multi-omics discovery of diagnostic biomarkers and drug-repurposing targets

   Clinical epigenetics·16 Jul 2026

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