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Rapamycin-preconditioned placenta-derived mesenchymal stem cells

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

Outcomes

2

Peripheral blood cell counts

upin mice1

1 study

  1. Rapamycin-preconditioned placenta-derived mesenchymal stem cells increase peripheral blood cell counts in mice.

    “rPD-MSCs better enhance hematopoietic recovery, restore bone marrow cellularity, and increase peripheral blood cell counts by elevating the secretion of hematopoietic cytokines compared to non-preconditioned cells.”

    Animalsin irradiated ICR/CD1 mice compared to non-preconditioned cellswhole blood21 days

    Preconditioning with Rapamycin Improves Therapeutic Potential of Placenta-Derived Mesenchymal Stem Cells in Mouse Model of Hematopoietic Acute Radiation Syndrome

    International journal of molecular sciences17 May 2025

More on Peripheral blood cell counts

Bone marrow cellularity

upin mice1

1 study

  1. Rapamycin-preconditioned placenta-derived mesenchymal stem cells improve bone marrow cellularity in mice.

    “rPD-MSCs better enhance hematopoietic recovery, restore bone marrow cellularity, and increase peripheral blood cell counts by elevating the secretion of hematopoietic cytokines compared to non-preconditioned cells.”

    Animalsin irradiated ICR/CD1 mice compared to non-preconditioned cellsbone marrow21 days

    Preconditioning with Rapamycin Improves Therapeutic Potential of Placenta-Derived Mesenchymal Stem Cells in Mouse Model of Hematopoietic Acute Radiation Syndrome

    International journal of molecular sciences17 May 2025

More on Bone marrow cellularity

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