RAB7-APT2 mrna lnp

Intervention1 paper4 findings

Animals1

Outcomes

4

Bone regeneration

upin rats1Very low certainty

1 study

RAB7-APT2 mrna lnp improves bone regeneration in rats.
Animalsaged rat defect model
A dual-targeting mRNA lipid nanoparticle restores ABCA1-dependent cholesterol homeostasis to promote repair of age-related bone defects · Bioactive materials · 20 Aug 2026

Osteogenesis

upin cells1Very low certainty

1 study

RAB7-APT2 mrna lnp improves osteogenesis in cells.
Cellsin vitro
A dual-targeting mRNA lipid nanoparticle restores ABCA1-dependent cholesterol homeostasis to promote repair of age-related bone defects · Bioactive materials · 20 Aug 2026

Autophagy

upin cells1Very low certainty

1 study

RAB7-APT2 mrna lnp activates autophagy in cells.
Cellsin aged BMSCs
A dual-targeting mRNA lipid nanoparticle restores ABCA1-dependent cholesterol homeostasis to promote repair of age-related bone defects · Bioactive materials · 20 Aug 2026

Cellular senescence

downin cells1Very low certainty

1 study

RAB7-APT2 mrna lnp decreases cellular senescence in cells.
Cellsin aged BMSCs
A dual-targeting mRNA lipid nanoparticle restores ABCA1-dependent cholesterol homeostasis to promote repair of age-related bone defects · Bioactive materials · 20 Aug 2026

Cellular senescence →

Latest

1

Bioactive MaterialsAnimals29 Aug

A dual-targeting mRNA lipid nanoparticle restores ABCA1-dependent cholesterol homeostasis to promote repair of age-related bone defects

Bones and joints