Prodigiosin

1. Prodigiosin inhibits cellular senescence in mice.

   “Furthermore, PDN inhibits the senescent state of AMs in aging mice.”

   Animalslung

   Prodigiosin targeting alveolar macrophages to mitigate the inflammatory response induced by H9N2 viral infection

   Veterinary microbiology·8 Dec 2025

More on Cellular senescence

1. Prodigiosin inhibits wnt/β-catenin signalling in mice.

   “Mechanistically, PDN downregulates the Wnt/β-catenin pathway while preserving mitochondrial function.”

   Animalsin a mouse model of H9N2 AIV infection

   Prodigiosin targeting alveolar macrophages to mitigate the inflammatory response induced by H9N2 viral infection

   Veterinary microbiology·8 Dec 2025

More on Wnt/β-catenin signalling

1. Prodigiosin decreases histopathological lung damage in mice.

   “PDN leads to a substantial decline in pro-inflammatory cytokine production, mitigates histopathological lung damage.”

   Animalsin a mouse model of H9N2 AIV infection

   Prodigiosin targeting alveolar macrophages to mitigate the inflammatory response induced by H9N2 viral infection

   Veterinary microbiology·8 Dec 2025

1. Prodigiosin decreases mortality in mice.

   “PDN significantly alleviates both morbidity and mortality in a mouse model of H9N2 AIV infection.”

   Animalsin a mouse model of H9N2 AIV infection

   Prodigiosin targeting alveolar macrophages to mitigate the inflammatory response induced by H9N2 viral infection

   Veterinary microbiology·8 Dec 2025