Pramlintide

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab

Humans1

Outcomes

Diastolic blood pressure

downin humans1

1 study

Pramlintide decreases diastolic blood pressure in humans (-5.7 vs -3.4% per kg, BH P=0.029).
“and diastolic blood pressure (-5.7 vs -3.4% per kg, BH P=0.029)”
Humansafter normalization for weight loss, compared with tirzepatide in type 2 diabetes receiving basal insulin6 months
Real-World EHR Signals from a Cohort of Blinded Incretin Trial Participants Motivate Novel Indication Opportunities
Preprints.org3 Sep 2026Preprint