Cagrisema

InterventionPhase 3

3 papers3 findings

  • 1 lab
  • 9 trials
  • 1 of 9 trials sponsored by its developers
  • Humans1

Outcomes

3

Creatinine

downin humans1

1 study
  1. Cagrisema decreases creatinine in humans (-17.4% vs -2.4%, BH P=0.020).

    “creatinine (-17.4% vs -2.4%, BH P=0.020), and greater increases in eGFR (+26.4% vs +6.4%, BH P=0.030)”

    Humanscompared with matched empagliflozin-treated patients6 months

    Real-World EHR Signals from a Cohort of Blinded Incretin Trial Participants Motivate Novel Indication Opportunities

    Preprints.org3 Sep 2026Preprint

More on Creatinine

Mean arterial pressure

downin humans1

1 study
  1. Cagrisema decreases mean arterial pressure in humans (-12.0% vs -1.0%, BH P<0.001).

    “larger reductions in weight (-7.7% vs -3.5%, P=0.048), mean arterial pressure (-12.0% vs -1.0%, BH P<0.001)”

    Humanscompared with matched empagliflozin-treated patients6 months

    Real-World EHR Signals from a Cohort of Blinded Incretin Trial Participants Motivate Novel Indication Opportunities

    Preprints.org3 Sep 2026Preprint

More on Mean arterial pressure

Estimated glomerular filtration rate

upin humans1

1 study
  1. Cagrisema increases estimated glomerular filtration rate in humans (+26.4% vs +6.5%, BH P=0.028).

    “larger increases in estimated glomerular filtration rate (+26.4% vs +6.5%, BH P=0.028)”

    Humanscompared with matched tirzepatide-treated patients6 months

    Real-World EHR Signals from a Cohort of Blinded Incretin Trial Participants Motivate Novel Indication Opportunities

    Preprints.org3 Sep 2026Preprint

More on Estimated glomerular filtration rate

Trials

9

In trials

Trial sponsors

Latest

Nov 2025: 0Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 0Sep 2026: 2Oct 2026: 03 in 12 months