Poor oral health
2 papers7 findings
- 2 independent labs in 2 countries
- Funders: Agence Nationale de la Recherche and 4 more
- Humans2
Outcomes
1Coronary artery calcium
no changein humans1
1 study
Coronary artery calcium
no changein humans1
Poor oral health has no effect on coronary artery calcium in humans.
“Coronary artery calcium and thoracic aortic calcium were not associated with tooth loss or damaged teeth.”
Humans
The journals of gerontology. Series A, Biological sciences and medical sciences31 Jan 2024
Associations
5Dementia
upin humans1
1 study
Dementia
upin humans1
Poor oral health is associated with dementia in humans.
“painful gums and dentures demonstrated additive interactions with genetic risk, although no multiplicative interaction was observed.”
Humansjoint effects with genetic riskn = 364,557
Association of Oral health and Genetic Risk with Incidence of Dementia
GSA 2025 abstract31 Dec 2025
Poor oral health raises the risk of dementia in humans.
“Oral health problems, particularly painful gums and dentures, were associated with increased risk of ACD, AD, and VaD.”
Humansn = 364,557
Association of Oral health and Genetic Risk with Incidence of Dementia
GSA 2025 abstract31 Dec 2025
Brain tissue loss
upin humans1
1 study
Brain tissue loss
upin humans1
Poor oral health is associated with brain tissue loss in humans.
“However, aortic valve calcification and brain tissue loss were higher in those who had more teeth with exposed pulp.”
Humans
The journals of gerontology. Series A, Biological sciences and medical sciences31 Jan 2024
Aortic valve calcification
upin humans1
1 study
Aortic valve calcification
upin humans1
Poor oral health is associated with aortic valve calcification in humans.
“However, aortic valve calcification and brain tissue loss were higher in those who had more teeth with exposed pulp.”
Humans
The journals of gerontology. Series A, Biological sciences and medical sciences31 Jan 2024
Body mass index
downin humans1
1 study
Body mass index
downin humans1
Poor oral health is associated with body mass index in humans.
“The number of teeth with exposed pulp was associated with higher inflammation, as measured by cytokine levels and white blood cell counts, and lower body mass index.”
Humans
The journals of gerontology. Series A, Biological sciences and medical sciences31 Jan 2024
Inflammation
upin humans1
1 study
Inflammation
upin humans1
Poor oral health is associated with inflammation in humans.
“The number of teeth with exposed pulp was associated with higher inflammation, as measured by cytokine levels and white blood cell counts, and lower body mass index.”
Humans
The journals of gerontology. Series A, Biological sciences and medical sciences31 Jan 2024
Funding
1 grant since 2025Japan Society for the Promotion of ScienceJP¥4.4m