Polyamine-rich diet

1. Polyamine-rich diet has no effect on spermidine in humans.

   “Blood spermidine did not increase in either group.”

   Human trialnattowhole blood12 monthsmalesn = 30

   Polyamine-Rich Diet Elevates Blood Spermine Levels and Inhibits Pro-Inflammatory Status: An Interventional Study

   Medical sciences (Basel, Switzerland)·Mar 29, 2021

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1. Polyamine-rich diet decreases LFA-1 in humans (OR 3.927 (95% CI 1.116-13.715), p = 0.032).

   “Contingency table analysis revealed that the odds ratio to decrease LFA-1 by increased polyamine intake was 3.927 (95% CI 1.116-13.715) (p = 0.032) when the effect of acute inflammation was excluded.”

   Human trialnattomonocytes12 monthsmalesn = 30

   Polyamine-Rich Diet Elevates Blood Spermine Levels and Inhibits Pro-Inflammatory Status: An Interventional Study

   Medical sciences (Basel, Switzerland)·Mar 29, 2021

More on LFA-1

1. Polyamine-rich diet increases spermine in humans (1.12 ± 0.29 times, p = 0.019).

   “The mean blood spermine level in the intervention group gradually rose to 1.12 ± 0.29 times the pre-intervention level after 12 months, and were significantly higher (p = 0.019) than those in the control group.”

   Human trialnattowhole blood12 monthsmalesn = 30

   Polyamine-Rich Diet Elevates Blood Spermine Levels and Inhibits Pro-Inflammatory Status: An Interventional Study

   Medical sciences (Basel, Switzerland)·Mar 29, 2021

More on Spermine