Plasma exosomes of old individuals
1 paper3 findings
- 1 lab in 1 country
- Cells1
Outcomes
3NF-κB signalling
upin human cells1
1 study
NF-κB signalling
upin human cells1
Plasma exosomes of old individuals increase NF-κB signalling in human cells (P=0.0014).
“Furthermore, a significant difference was seen in p-NF-κB levels between O-exo and Y-exo at the concentration of 10 μg/mL (P=0.0014).”
Cells10 μg/mL
Current topics in medicinal chemistry1 Jan 2025
Inflammation
upin human cells1
1 study
Inflammation
upin human cells1
Plasma exosomes of old individuals increase inflammation in human cells (P<0.01).
“The HSCs treated with 10 μg/mL O-exo increased protein and mRNA expression of IL-1β and IL-6 compared to Y-exo at 10 μg/mL concentration (P<0.01).”
Cells10 μg/mL
Current topics in medicinal chemistry1 Jan 2025
Stem cell differentiation
upin human cells1
1 study
Stem cell differentiation
upin human cells1
Plasma exosomes of old individuals increase stem cell differentiation in human cells (P<0.001).
“The lineage-specific markers CD41 and CD38 expression were increased after exposure to O-exo compared to Y-exo at the concentration of 10 μg/mL (P<0.001).”
Cells10 μg/mL
Current topics in medicinal chemistry1 Jan 2025
Latest
Current Topics in Medicinal Chemistry
The Effects of Plasma Exosomes of Young Individuals Compared to Old Ones on Age-Related Inflammation and Lineage Differentiation of CD34⁺ Umbilical Cord Blood Hematopoietic Stem Cells
Experiments in human cellsStem cell differentiation