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Pi3k/akt inhibitor

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funder: Ministero della Salute
  • Humans1

Outcomes

1

Cellular senescence

downin human cells1

1 study

  1. Pi3k/akt inhibitor decreases cellular senescence in human cells.

    “PI3K/AKT inhibition contrasted senescence processes induced by cytokines in psoriatic keratinocytes.”

    Cellsin cytokine-treated psoriatic keratinocytes

    RAS-activated PI3K/AKT signaling sustains cellular senescence via P53/P21 axis in experimental models of psoriasis

    Journal of dermatological scienceMar 7, 2024

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