Phenylacetic acid

Intervention1 paper2 findings

  • Animals1

Outcomes

2

Atherosclerosis

upin mice1Low certainty

1 study
  1. Phenylacetic acid increases atherosclerosis in mice.

    Animalsatheroprone Ldlr -/- mice with ABx-suppressed microbiota50 mg/kg/d12 weeks

    Intestinal Microbiota-derived Phenylacetic acid Accelerates Perivascular Adipose Tissue Senescence and Atherosclerosis in Aging · AHA Scientific Sessions 2025 abstract · 3 Nov 2025

Atherosclerosis →

Cellular senescence

upin mice1Low certainty

1 study
  1. Phenylacetic acid increases cellular senescence in mice.

    Animalsperivascular adipose tissue

    Intestinal Microbiota-derived Phenylacetic acid Accelerates Perivascular Adipose Tissue Senescence and Atherosclerosis in Aging · AHA Scientific Sessions 2025 abstract · 3 Nov 2025

Cellular senescence →

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