Phenolamides
1 paper4 findings
- 1 lab in 1 country
- Funders: National Natural Science Foundation of China and 2 more
- Model organisms1
Outcomes
4Oxidative stress and ROS signalling
downin human cells1
1 study
Oxidative stress and ROS signalling
downin human cells1
Phenolamides decrease oxidative stress and ROS signalling in human cells.
“Western blot revealed that compounds 2 and 4 alleviated the oxidative stress through up-regulation of the expression of Nrf2 and HO-1 protein”
CellsMPP+-induced SH-SY5Y cells
Journal of agricultural and food chemistry1 Apr 2025
Locomotor behavior
upin flies1
1 study
Locomotor behavior
upin flies1
Phenolamides improve locomotor behavior in flies.
“extended the lifespan, dopamine and ATP levels, locomotor behavior, and olfactory ability of the PINK1B9 flies”
Model organismsin PINK1B9 flies
Journal of agricultural and food chemistry1 Apr 2025
Lifespan
upin flies1
1 study
Lifespan
upin flies1
Phenolamides extend lifespan in flies.
“Moreover, compounds 2 and 4 extended the lifespan, dopamine and ATP levels, locomotor behavior, and olfactory ability of the PINK1B9 flies”
Model organismsin PINK1B9 flies
Journal of agricultural and food chemistry1 Apr 2025
Neurotoxicity
downin human cells1
1 study
Neurotoxicity
downin human cells1
Phenolamides protect against neurotoxicity in human cells.
“All four phenolamides displayed a neuroprotective effect against 1-methyl-4-phenylpyridinium -induced SH-SY5Y cells model”
CellsMPP+-induced SH-SY5Y cells
Journal of agricultural and food chemistry1 Apr 2025
Latest
Journal of Agricultural and Food Chemistry
Phenolamides from Rootstocks of Lycium ruthenicum Murr by Ligand Fishing and Their Neuroprotective Effects
Experiments in fliesInterventions