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Pharmacological HSF1 enhancement

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Animals1

Outcomes

3

Cognitive function

upin mice1

1 study

  1. Pharmacological HSF1 enhancement improves cognitive function in mice.

    “Moreover, pharmacologically enhancing HSF1 improved BAT senescence, metabolic decline, and cognitive dysfunction in aged mice.”

    Animals

    Thermogenic Adipose ADH5 Counteracts Age-related Metabolic Decline

    bioRxiv : the preprint server for biology9 Jul 2025Preprint

Metabolic function

upin mice1

1 study

  1. Pharmacological HSF1 enhancement improves metabolic function in mice.

    “Moreover, pharmacologically enhancing HSF1 improved BAT senescence, metabolic decline, and cognitive dysfunction in aged mice.”

    Animals

    Thermogenic Adipose ADH5 Counteracts Age-related Metabolic Decline

    bioRxiv : the preprint server for biology9 Jul 2025Preprint

Cellular senescence

downin mice1

1 study

  1. Pharmacological HSF1 enhancement decreases cellular senescence in mice.

    “Moreover, pharmacologically enhancing HSF1 improved BAT senescence, metabolic decline, and cognitive dysfunction in aged mice.”

    Animalsbrown adipose tissue

    Thermogenic Adipose ADH5 Counteracts Age-related Metabolic Decline

    bioRxiv : the preprint server for biology9 Jul 2025Preprint

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