Peroxiredoxin 6

Intervention

1 paper2 findings

  • 1 lab in 1 country
  • Funders: National Eye Institute and 1 more
  • Cells1

Outcomes

2

Lens transparency

upin mice1

1 study
  1. Peroxiredoxin 6 improves lens transparency in mice.

    “TAT-HA-Prdx6 delivery inhibited H2O2-induced Nlrp3 activation and preserved lens transparency”

    AnimalsH2O2-induced oxidative stressTAT-HA-Prdx6 recombinant fusion proteinlens

    TXNIP-Deficiency and Prdx6 Delivery Inhibit Aging/Oxidative Stress-Driven TXNIP-Nlrp3 Inflammasome Activation and Mitigate Pyroptosis in Lens Epithelial Cells

    Antioxidants (Basel, Switzerland)28 Jan 2026

NLRP3 inflammasome

downin mice1

1 study
  1. Peroxiredoxin 6 inhibits NLRP3 inflammasome in mice.

    “TAT-HA-Prdx6 delivery inhibited H2O2-induced Nlrp3 activation and preserved lens transparency”

    AnimalsH2O2-induced oxidative stressTAT-HA-Prdx6 recombinant fusion proteinlens

    TXNIP-Deficiency and Prdx6 Delivery Inhibit Aging/Oxidative Stress-Driven TXNIP-Nlrp3 Inflammasome Activation and Mitigate Pyroptosis in Lens Epithelial Cells

    Antioxidants (Basel, Switzerland)28 Jan 2026

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