AgingResearch.NewsJoin free

PAR1 inhibitor

Intervention

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Natural Science Foundation of China and 2 more
  • Animals1

Outcomes

1

Non-small cell lung cancer progression

downin human cells1

1 study

  1. PAR1 inhibitor decreases non-small cell lung cancer progression in human cells.

    “Knocking down MMP1 or using PAR1 inhibitors reduced the tumor-promoting effects of DHLF-derived exosomes in vivo and in vitro.”

    Cellsin vivo and in vitro

    Senescent lung fibroblasts in idiopathic pulmonary fibrosis facilitate non-small cell lung cancer progression by secreting exosomal MMP1

    Oncogene11 Dec 2024

More on Non-small cell lung cancer progression

Latest

Related