Palmitoleic acid

2 papers2 findings

2 independent labs in 1 country

Animals1
Model organisms1

Outcomes

2

Lifespan

upin worms1

1 study

Palmitoleic acid extends lifespan in worms.
“exogenous supplementation of 1 mM oleic acid (OA) and palmitoleic acid (POA) restored nhr-49, fat-5, fat-6 and fat-7 mutants-induced shortened lifespan phenotype.”
Model organismsnhr-49, fat-5, fat-6 and fat-7 mutants1 mM
Streptococcus thermophilus remodels lipid metabolism to extend healthspan in Caenorhabditis elegans through NHR-49-Delta-9 desaturase axis
GeroScience15 Oct 2026

Peripheral neuropathy

downin mice1

1 study

Palmitoleic acid decreases peripheral neuropathy in mice.
“Palmitoleic acid improved peripheral neuropathy in diabetic mice”
Animalsin diabetic (db/db) mice
The Effects and Mechanisms of Caloric Restriction on Diabetic Peripheral Neuropathy
ADA Scientific Sessions 2025 abstract13 Jun 2025

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Streptococcus thermophilus remodels lipid metabolism to extend healthspan in Caenorhabditis elegans through NHR-49-Delta-9 desaturase axis

Experiments in wormsInterventions

Nutrients12 Jun

Maternal palmitoleic acid supplementation attenuates neurodegenerative programming in aged offspring exposed to gestational diabetes

Experiments in animalsInterventions

AAIC 2025 Abstract26 Dec

Cerebrospinal fluid fatty acids are better predictors of mild cognitive impairment than Aβ ₄₂ /tau ratio

Case-control study in peopleTau

ADA Scientific Sessions 2025 Abstract13 Jun

The Effects and Mechanisms of Caloric Restriction on Diabetic Peripheral Neuropathy

Experiments in miceDietary restriction