Pachymic acid

  • 1 lab in 1 country
  • Funders: Department of Education of Guizhou Province and 2 more
  • Animals1

Outcomes

2

Senile osteoporosis

downin mice1

1 study
  1. Pachymic acid protects against senile osteoporosis in mice.

    “promoted bone formation while inhibiting bone resorption, preventing bone loss, and ameliorating bone microstructure deterioration in senile osteoporosis (SOP) mice.”

    Animalsin SOP mice

    Pachymic acid targets PDIA6 to delay mesenchymal stem cell senescence through the G6PD/STAT3 signaling axis and prevent senile osteoporosis

    Journal of advanced research16 Feb 2026

More on Senile osteoporosis

Cellular senescence

downin human cells1

1 study
  1. Pachymic acid inhibits cellular senescence in human cells.

    “PA significantly reversed cell cycle arrest, reduced the accumulation of reactive oxygen species, and inhibited the production of senescence-associated β-galactosidase, and expression of the senescence markers p21 and p16, in senescent human MSCs.”

    Cellsin senescent human MSCs

    Pachymic acid targets PDIA6 to delay mesenchymal stem cell senescence through the G6PD/STAT3 signaling axis and prevent senile osteoporosis

    Journal of advanced research16 Feb 2026

More on Cellular senescence

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