Pachymic acid
- 1 lab in 1 country
- Funders: Department of Education of Guizhou Province and 2 more
- Animals1
Outcomes
2Senile osteoporosis
downin mice1
1 study
Senile osteoporosis
downin mice1
Pachymic acid protects against senile osteoporosis in mice.
“promoted bone formation while inhibiting bone resorption, preventing bone loss, and ameliorating bone microstructure deterioration in senile osteoporosis (SOP) mice.”
Animalsin SOP mice
Journal of advanced research16 Feb 2026
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Pachymic acid inhibits cellular senescence in human cells.
“PA significantly reversed cell cycle arrest, reduced the accumulation of reactive oxygen species, and inhibited the production of senescence-associated β-galactosidase, and expression of the senescence markers p21 and p16, in senescent human MSCs.”
Cellsin senescent human MSCs
Journal of advanced research16 Feb 2026
Latest
1 in 12 monthsJournal of Advanced Research
Pachymic acid targets PDIA6 to delay mesenchymal stem cell senescence through the G6PD/STAT3 signaling axis and prevent senile osteoporosis
Experiments in miceBones and joints