Ormeloxifene

1. Ormeloxifene improves tamoxifen sensitivity in human cells.

   CellsMCF-7

   Ormeloxifene, a non-steroidal selective estrogen receptor modulator induces senescence in breast cancer cells · Molecular biology reports · 1 Oct 2026

1. Ormeloxifene increases CDKN1A in human cells.

   CellsMCF-7

   Ormeloxifene, a non-steroidal selective estrogen receptor modulator induces senescence in breast cancer cells · Molecular biology reports · 1 Oct 2026

CDKN1A →

1. Ormeloxifene decreases CDK4 in human cells.

   CellsMCF-7

   Ormeloxifene, a non-steroidal selective estrogen receptor modulator induces senescence in breast cancer cells · Molecular biology reports · 1 Oct 2026

CDK4 →

1. Ormeloxifene decreases cell viability in human cells (IC50 values ranging from 7 to 9 μM).

   CellsMCF-7 and MDA-MB-231 cells

   Ormeloxifene, a non-steroidal selective estrogen receptor modulator induces senescence in breast cancer cells · Molecular biology reports · 1 Oct 2026