Oophorectomy
Intervention2 papers2 findings
Outcomes
2Overall survival
upin humans1
1 study
Overall survival
upin humans1
Oophorectomy improves overall survival in humans.
Reviewin individuals with pathogenic variants in BRCA1 and BRCA2
Survival associated with recommended risk-reducing interventions for individuals with pathogenic variants in BRCA1/2 · Gynecologic oncology · 22 Sep 2026
Dementia
no changein humans1Low certainty
1 study
Dementia
no changein humans1Low certainty
Oophorectomy has no effect on dementia in humans (0.99, 95% CI 0.88-1.12).
“nor did bilateral oophorectomy alone (4 studies; 0.99, 95% CI 0.88-1.12; I 2 = 75.6%).”
Reviewalone
Associations of Hysterectomy and Oophorectomy with Dementia Risk: A Systematic Review and Meta-Analysis of Observational Studies · Journal of clinical medicine · 17 Sep 2026
Latest
2Journal of Clinical MedicineReview