Oophorectomy

Intervention2 papers2 findings

Outcomes

2

Overall survival

upin humans1

1 study
  1. Oophorectomy improves overall survival in humans.

    Reviewin individuals with pathogenic variants in BRCA1 and BRCA2

    Survival associated with recommended risk-reducing interventions for individuals with pathogenic variants in BRCA1/2 · Gynecologic oncology · 22 Sep 2026

Dementia

no changein humans1Low certainty

1 study
  1. Oophorectomy has no effect on dementia in humans (0.99, 95% CI 0.88-1.12).

    “nor did bilateral oophorectomy alone (4 studies; 0.99, 95% CI 0.88-1.12; I 2 = 75.6%).”

    Reviewalone

    Associations of Hysterectomy and Oophorectomy with Dementia Risk: A Systematic Review and Meta-Analysis of Observational Studies · Journal of clinical medicine · 17 Sep 2026

Dementia →

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