Nora virus

Intervention

3 papers6 findings

  • 1 lab in 1 country
  • Funders: Agence Nationale de la Recherche and 4 more
  • Model organisms3

Outcomes

3

Intestinal barrier function

downin flies3

3 studies
  1. Nora virus impairs intestinal barrier function in flies.

    “the virus is then detected in enterocytes, which correlates with a disruption of the intestinal barrier function in aged flies.”

    Model organismsintestinal epithelium

    Nora virus proliferates in dividing intestinal stem cells and thereby sensitizes Drosophila flies to Pseudomonas aeruginosa intestinal infection and to oxidative stress

    eLife1 Apr 2026Preprint

  2. Nora virus impairs intestinal barrier function in flies.

    “the virus is then detected in enterocytes, which correlates with a disruption of the intestinal barrier function in aged flies.”

    Model organismsNora virus infectiongut epithelium

    Nora virus proliferates in dividing intestinal stem cells and thereby sensitizes Drosophila flies to Pseudomonas aeruginosa intestinal infection and to oxidative stress

    eLife1 Apr 2025Preprint

  3. Nora virus impairs intestinal barrier function in flies.

    “correlates with a disruption of the intestinal barrier function in aged flies.”

    Model organismsintestine

    Nora virus proliferates in dividing intestinal stem cells and sensitizes flies to intestinal infection and oxidative stress

    eLife1 Apr 2025Preprint

Sensitivity to Pseudomonas aeruginosa infection and oxidative stress

upin flies1

1 study
  1. Nora virus increases sensitivity to Pseudomonas aeruginosa infection and oxidative stress in flies.

    “the presence of Nora virus in the gut epithelium promotes the sensitivity to this bacterial pathogen as well as to an ingested oxidizing xenobiotic.”

    Model organismsingested Pseudomonas aeruginosa or oxidizing xenobioticgut epithelium

    Nora virus proliferates in dividing intestinal stem cells and thereby sensitizes Drosophila flies to Pseudomonas aeruginosa intestinal infection and to oxidative stress

    eLife1 Apr 2026Preprint

Infection sensitivity

upin flies1

1 study
  1. Nora virus increases infection sensitivity in flies.

    “presence of Nora virus in the gut epithelium promotes the sensitivity to this bacterial pathogen as well as to an ingested oxidizing xenobiotic.”

    Model organismsgut epithelium

    Nora virus proliferates in dividing intestinal stem cells and sensitizes flies to intestinal infection and oxidative stress

    eLife1 Apr 2025Preprint

Associations

1

Pseudomonas aeruginosa infection

upin flies1

1 study
  1. Nora virus raises the risk of Pseudomonas aeruginosa infection in flies.

    “Nora virus in the gut epithelium promotes the sensitivity to this bacterial pathogen as well as to an ingested oxidizing xenobiotic.”

    Model organismsgut epithelium

    Nora virus proliferates in dividing intestinal stem cells and thereby sensitizes Drosophila flies to Pseudomonas aeruginosa intestinal infection and to oxidative stress

    eLife1 Apr 2025Preprint

More on Pseudomonas aeruginosa infection

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