NKG2A blockade
1 paper3 findings
- 1 lab in 1 country
- Funder: National Institutes of Health
- Humans1
Outcomes
3Pulmonary fibrosis
downin mice1
1 study
Pulmonary fibrosis
downin mice1
NKG2A blockade decreases pulmonary fibrosis in mice.
“In vivo, therapeutic blockade of NKG2A restored NK cell function, promoted clearance of senescent fibroblasts, and promoted fibrosis resolution in the bleomycin-induced mouse model.”
Animalsbleomycin-induced pulmonary fibrosislung
Natural killer cell immunotherapy reverses lung fibrosis by eliminating senescent fibroblasts
Science translational medicine13 May 2026
Clearance of senescent fibroblasts
upin mice1
1 study
Clearance of senescent fibroblasts
upin mice1
NKG2A blockade increases clearance of senescent fibroblasts in mice.
“In vivo, therapeutic blockade of NKG2A restored NK cell function, promoted clearance of senescent fibroblasts, and promoted fibrosis resolution in the bleomycin-induced mouse model.”
Animalsbleomycin-induced pulmonary fibrosislung
Natural killer cell immunotherapy reverses lung fibrosis by eliminating senescent fibroblasts
Science translational medicine13 May 2026
NK cell function
upin mice1
1 study
NK cell function
upin mice1
NKG2A blockade improves NK cell function in mice.
“In vivo, therapeutic blockade of NKG2A restored NK cell function, promoted clearance of senescent fibroblasts, and promoted fibrosis resolution in the bleomycin-induced mouse model.”
Animalsbleomycin-induced pulmonary fibrosis
Natural killer cell immunotherapy reverses lung fibrosis by eliminating senescent fibroblasts
Science translational medicine13 May 2026