1 paper3 findings
Cognition, learning, and memory
upin mice1
Nano-eraser-based trim-away system improves cognition, learning, and memory in mice.
“Importantly, TN-PTBP1 treatment significantly improves cognition, learning, and memory, demonstrating true functional reversal of AD-associated deficits.”
AnimalsAlzheimer's disease model
Protein-targeting system improved learning and memory in mice
Cell biomaterials26 Aug 2026
Hippocampal neurogenesis
upin mice1
Nano-eraser-based trim-away system increases hippocampal neurogenesis in mice.
“restores hippocampal neurogenesis in AD mice.”
AnimalsAlzheimer's disease modelhippocampus
Protein-targeting system improved learning and memory in mice
Cell biomaterials26 Aug 2026
Functional neuron generation
upin human cells1
Nano-eraser-based trim-away system induces functional neuron generation in human cells.
“This non-genomic protein depletion induces astrocyte-to-neuron conversion, generates functional neurons in vitro and in human brain organoids, and restores hippocampal neurogenesis in AD mice.”
Cellshuman brain organoids
Protein-targeting system improved learning and memory in mice
Cell biomaterials26 Aug 2026
An experiment in Alzheimer's disease mice found that the system also restored new neuron formation in a brain region involved in memory.An experiment in Alzheimer's disease mice found that the system also restored new neuron formation in a brain region involved in memory.