Nampt-extracellular vesicles
1 paper4 findings
- 1 lab in 1 country
- Funders: Basic and Applied Basic Research Foundation of Guangdong Province and 3 more
- Animals1
Outcomes
4Oxidative phosphorylation
upin human cells1
1 study
Oxidative phosphorylation
upin human cells1
Nampt-extracellular vesicles increase oxidative phosphorylation in human cells.
“rescued impairments of oxidative phosphorylation in both mouse and human AAA models”
Cellsin mouse and human AAA models
Bioactive materials14 Dec 2023
DNA damage response
downin human cells1
1 study
DNA damage response
downin human cells1
Nampt-extracellular vesicles decrease DNA damage response in human cells.
“NAMPT-EVs not only repressed injuries, such as cell senescence and DNA damage, but also rescued impairments of oxidative phosphorylation in both mouse and human AAA models”
Cellsin mouse and human AAA models
Bioactive materials14 Dec 2023
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Nampt-extracellular vesicles decrease cellular senescence in human cells.
“NAMPT-EVs not only repressed injuries, such as cell senescence and DNA damage, but also rescued impairments of oxidative phosphorylation in both mouse and human AAA models”
Cellsin mouse and human AAA models
Bioactive materials14 Dec 2023
Abdominal aortic aneurysm
downin mice1
1 study
Abdominal aortic aneurysm
downin mice1
Nampt-extracellular vesicles protect against abdominal aortic aneurysm in mice.
“NAMPT-extracellular vesicles (EVs) derived from mesenchymal stem cells restored NAMPT levels, and offered protection against AAA.”
Animalsin mouse model of AAA induced by Angiotensin II
Bioactive materials14 Dec 2023