Multicomponent program

Multicomponent program has no effect on psychology in humans.

“Cognition and psychology showed no significant between-group effects after Holm adjustment.”

Human trialBetween-group comparison after Holm adjustmentface-to-face group program80 minutes, twice weekly12 months65% womensn = 294

Effectiveness of a multicomponent intervention on intrinsic capacity among community-dwelling adults aged ≥75 years: A prospective controlled study with 12-month follow-up

Experimental gerontology·22 Apr 2026

Multicomponent program has no effect on cognitive function in humans.

“Cognition and psychology showed no significant between-group effects after Holm adjustment.”

Human trialBetween-group comparison after Holm adjustmentface-to-face group program80 minutes, twice weekly12 months65% womensn = 294

Effectiveness of a multicomponent intervention on intrinsic capacity among community-dwelling adults aged ≥75 years: A prospective controlled study with 12-month follow-up

Experimental gerontology·22 Apr 2026

Multicomponent program is associated with vitality in humans (β = 0.52, 95% CI 0.16–0.88 at 6 months only).

“Vitality improved at 6 months only (β = 0.52, 95% CI 0.16-0.88; Holm P = 0.009).”

Human trialCommunity-dwelling adults; compared with health guidance and usual careface-to-face group program80 minutes, twice weekly6 months65% womensn = 294

Effectiveness of a multicomponent intervention on intrinsic capacity among community-dwelling adults aged ≥75 years: A prospective controlled study with 12-month follow-up

Experimental gerontology·22 Apr 2026

Multicomponent program is associated with locomotion in humans (β = 2.05, 95% CI 1.46–2.63 at 12 months).

“Locomotion improved (β = 1.68, 95% CI 1.11-2.25 at 6 months; β = 2.05, 95% CI 1.46-2.63 at 12 months; both Holm P < 0.001).”

Human trialCommunity-dwelling adults; compared with health guidance and usual careface-to-face group program80 minutes, twice weekly12 months65% womensn = 294

Effectiveness of a multicomponent intervention on intrinsic capacity among community-dwelling adults aged ≥75 years: A prospective controlled study with 12-month follow-up

Experimental gerontology·22 Apr 2026

Multicomponent program is associated with intrinsic capacity in humans (β = 0.33, 95% CI 0.10–0.56 at 12 months).

“Adjusted IC was higher in the intervention group at 6 months (β = 0.33, 95% CI 0.11-0.56; Holm P = 0.008) and 12 months”

Human trialCommunity-dwelling adults; compared with health guidance and usual careface-to-face group program80 minutes, twice weekly12 months65% womensn = 294

Effectiveness of a multicomponent intervention on intrinsic capacity among community-dwelling adults aged ≥75 years: A prospective controlled study with 12-month follow-up

Experimental gerontology·22 Apr 2026