ML216
- 1 lab in 1 country
- Funders: Chinese Academy of Medical Sciences and 1 more
- Animals1
- Cells1
Outcomes
3Pulmonary fibrosis
downin mice1
1 study
Pulmonary fibrosis
downin mice1
ML216 decreases pulmonary fibrosis in mice.
“ML216 enhances pulmonary function by lowering the levels of senescence and fibrosis in both aged mice and a mouse model of bleomycin-induced idiopathic pulmonary fibrosis.”
Animalsin both aged mice and a mouse model of bleomycin-induced idiopathic pulmonary fibrosis
ML216 Prevents DNA Damage-Induced Senescence by Modulating DBC1-BLM Interaction
CellsDec 29, 2022
Pulmonary function
upin mice1
1 study
Pulmonary function
upin mice1
ML216 improves pulmonary function in mice.
“ML216 enhances pulmonary function by lowering the levels of senescence and fibrosis in both aged mice and a mouse model of bleomycin-induced idiopathic pulmonary fibrosis.”
Animalsin both aged mice and a mouse model of bleomycin-induced idiopathic pulmonary fibrosis
ML216 Prevents DNA Damage-Induced Senescence by Modulating DBC1-BLM Interaction
CellsDec 29, 2022
Cellular senescence
downin mouse cells1
1 study
Cellular senescence
downin mouse cells1
ML216 inhibits cellular senescence in mouse cells.
“ML216 promotes DBC1-BLM interaction, which aids in the preservation of BLM following DNA damage and suppresses senescence.”
Cellsfollowing DNA damage
ML216 Prevents DNA Damage-Induced Senescence by Modulating DBC1-BLM Interaction
CellsDec 29, 2022
Latest
1 in 12 monthsInternational Journal of Molecular Sciences
ML216 Alleviates Age-Related Cardiac Fibrosis by Suppressing TGF-β1 Signaling Pathway
Experiments in miceTGF-β signalling
Cells
ML216 Prevents DNA Damage-Induced Senescence by Modulating DBC1-BLM Interaction
Experiments in cellsInterventions