MK-8722
Intervention1 paper4 findingsPubChem 89558344
- Animals1
Outcomes
4Long-term potentiation
no changein mice1
1 study
Long-term potentiation
no changein mice1
MK-8722 has no effect on long-term potentiation in mice.
Animalsin APP/PS1 micehippocampus
Pan-AMPK activator MK-8722 improves spatial memory in Alzheimer's model mice · Journal of neurochemistry · 1 Oct 2026
Dendritic spine maturation
upin mice1
1 study
Dendritic spine maturation
upin mice1
MK-8722 increases dendritic spine maturation in mice.
Animalsin APP/PS1 micehippocampus
Pan-AMPK activator MK-8722 improves spatial memory in Alzheimer's model mice · Journal of neurochemistry · 1 Oct 2026
Spatial memory
upin mice1
1 study
Spatial memory
upin mice1
MK-8722 improves spatial memory in mice.
Animalsin APP/PS1 mice
Pan-AMPK activator MK-8722 improves spatial memory in Alzheimer's model mice · Journal of neurochemistry · 1 Oct 2026
AMPK signalling
upin mice1
1 study
AMPK signalling
upin mice1
MK-8722 activates AMPK signalling in mice.
Animalsin APP/PS1 miceliver
Pan-AMPK activator MK-8722 improves spatial memory in Alzheimer's model mice · Journal of neurochemistry · 1 Oct 2026
Latest
1Pan-AMPK activator MK-8722 improves spatial memory in Alzheimer's model mice
Systemic treatment activated liver AMPK, restored plasma metabolites, and enhanced dendritic spine maturation without altering hippocampal long-term potentiation.
Journal of neurochemistry · Nicol NI et al.