Mitochondrial hydrogen-supply system
1 paper5 findings
- 1 lab in 1 country
- Funders: China Postdoctoral Science Foundation and 1 more
- Animals1
Outcomes
5Bone-vascular coupled regeneration
upin mice1
1 study
Bone-vascular coupled regeneration
upin mice1
Mitochondrial hydrogen-supply system increases bone-vascular coupled regeneration in mice.
“following systemic administration, EMHS preferentially accumulates in bone and promotes bone-vascular coupled regeneration in aged mice with bone defects.”
Animalsbone defectsbone
Advanced materials (Deerfield Beach, Fla.)Jul 20, 2026
Neutrophil pro-repair phenotype
upin mouse cells1
1 study
Neutrophil pro-repair phenotype
upin mouse cells1
Mitochondrial hydrogen-supply system induces neutrophil pro-repair phenotype in mouse cells.
“EMHS restores the osteogenic potential of bone marrow mesenchymal stem cells (BMSCs), enhances endothelial angiogenic capacity, and biases neutrophils toward a pro-repair phenotype.”
Cellsneutrophil
Advanced materials (Deerfield Beach, Fla.)Jul 20, 2026
Osteogenic potential
upin mouse cells1
1 study
Osteogenic potential
upin mouse cells1
Mitochondrial hydrogen-supply system improves osteogenic potential in mouse cells.
“EMHS restores the osteogenic potential of bone marrow mesenchymal stem cells (BMSCs)”
Cellsbone marrow mesenchymal stem cell
Advanced materials (Deerfield Beach, Fla.)Jul 20, 2026
Senescence-associated phenotypes
downin mice1
1 study
Senescence-associated phenotypes
downin mice1
Mitochondrial hydrogen-supply system decreases senescence-associated phenotypes in mice.
“a mitochondrial hydrogen-supply system (EMHS) is developed that attenuates senescence-associated phenotypes in the aged bone regenerative niche”
Animalsbone regenerative niche
Advanced materials (Deerfield Beach, Fla.)Jul 20, 2026
Mitochondrial electron transport chain function
upin mouse cells1
1 study
Mitochondrial electron transport chain function
upin mouse cells1
Mitochondrial hydrogen-supply system improves mitochondrial electron transport chain function in mouse cells.
“the active hydrogen generated by EMHS infiltrates mitochondria in senescent cells, enabling the paired delivery of proton-electron equivalents to restore ETC function.”
Cellssenescent cells
Advanced materials (Deerfield Beach, Fla.)Jul 20, 2026