Materials Today Bio
Targeted RNA delivery alleviates bone loss in mice
In a mouse model of osteoporosis caused by ovary removal, bone-targeted engineered vesicles preserved bone structure and reduced bone-breakdown activity without causing…In a mouse model of osteoporosis caused by ovary removal, bone-targeted engineered vesicles preserved bone structure and reduced bone-breakdown activity without causing systemic toxicity.
Mouse studyBones and joints
Who was studiedMice with ovariectomy-induced osteoporosis
What changedBone-targeted RNA delivery reduced bone loss in mice with osteoporosis induced by ovary removal
The catchThe abstract provides no long-term safety data