AgingResearch.NewsJoin free

Mitochondrial transplantation + mitoquinone + melatonin

Intervention

1 paper3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: Tabriz University of Medical Sciences and 1 more
  • Animals1

Outcomes

3

Mitochondrial biogenesis (PGC-1α)

upin rats1

1 study

  1. Mitochondrial transplantation + mitoquinone + melatonin increases mitochondrial biogenesis (PGC-1α) in rats.

    “The triple therapy enhanced myocardial function, decreased creatine kinase-MB levels and improved mitochondrial function along with the expression of mitochondrial biogenesis genes in aged IR rats.”

    Animalsmyocardial ischaemia-reperfusion injurytriple therapyheart14 days prior to ischaemia and at reperfusionmalesn = 54

    Mitochondrial transplantation combined with mitoquinone and melatonin: A survival strategy against myocardial reperfusion injury in aged rats

    Experimental physiology31 Mar 2025

More on Mitochondrial biogenesis (PGC-1α)

Creatine kinase-MB

downin rats1

1 study

  1. Mitochondrial transplantation + mitoquinone + melatonin decreases creatine kinase-MB in rats.

    “The triple therapy enhanced myocardial function, decreased creatine kinase-MB levels and improved mitochondrial function along with the expression of mitochondrial biogenesis genes in aged IR rats.”

    Animalsmyocardial ischaemia-reperfusion injurytriple therapyheart14 days prior to ischaemia and at reperfusionmalesn = 54

    Mitochondrial transplantation combined with mitoquinone and melatonin: A survival strategy against myocardial reperfusion injury in aged rats

    Experimental physiology31 Mar 2025

More on Creatine kinase-MB

Myocardial function

upin rats1

1 study

  1. Mitochondrial transplantation + mitoquinone + melatonin improves myocardial function in rats.

    “The triple therapy enhanced myocardial function, decreased creatine kinase-MB levels and improved mitochondrial function along with the expression of mitochondrial biogenesis genes in aged IR rats.”

    Animalsmyocardial ischaemia-reperfusion injurytriple therapyheart14 days prior to ischaemia and at reperfusionmalesn = 54

    Mitochondrial transplantation combined with mitoquinone and melatonin: A survival strategy against myocardial reperfusion injury in aged rats

    Experimental physiology31 Mar 2025

Latest

Related