Maresin 1

1. Maresin 1 inhibits NF-κB signaling in rats.

   “MaR1 substantially inhibited the mRNA and protein expression of NF-κB p65 and κB inhibitor kinase β”

   Animalsafter splenectomyhippocampus

   Maresin1 ameliorates postoperative cognitive dysfunction in aged rats by potentially regulating the NF-κB pathway to inhibit astrocyte activation

   Experimental gerontology·Apr 13, 2023

More on NF-κB signaling

1. Maresin 1 decreases inflammation in rats.

   “MaR1 inhibited the mRNA and protein expression of several key proinflammatory cytokines-interleukin-1β, interleukin-6, and tumor necrosis factor-α”

   Animalsafter splenectomyhippocampus

   Maresin1 ameliorates postoperative cognitive dysfunction in aged rats by potentially regulating the NF-κB pathway to inhibit astrocyte activation

   Experimental gerontology·Apr 13, 2023

More on Inflammation

1. Maresin 1 inhibits astrocyte activation in rats.

   “MaR1 significantly alleviated the fluorescence intensity and protein expression of glial fibrillary acidic protein and central nervous system specific protein”

   Animalsafter splenectomycornu ammonis 1 region of the hippocampus

   Maresin1 ameliorates postoperative cognitive dysfunction in aged rats by potentially regulating the NF-κB pathway to inhibit astrocyte activation

   Experimental gerontology·Apr 13, 2023

More on Astrocyte activation

1. Maresin 1 decreases cognitive impairment in rats.

   “cognitive impairment of rats was significantly mitigated when MaR1 pretreatment was administered”

   Animalsafter splenectomyhippocampus

   Maresin1 ameliorates postoperative cognitive dysfunction in aged rats by potentially regulating the NF-κB pathway to inhibit astrocyte activation

   Experimental gerontology·Apr 13, 2023