Low-intensity exercise

2 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Animals1

Outcomes

Exercise capacity

upin mice1

1 study

Low-intensity exercise improves exercise capacity in mice (p < 0.01).
“maximum supported workload was maintained for high-intensity exercise (p > 0.05) and increased for low-intensity exercise (p < 0.01)”
Animals
Clock Gene Expression Modulation by Low- and High-Intensity Exercise Regimens in Aging Mice
International journal of molecular sciences8 Sep 2025

PER1

upin mice1

1 study

Low-intensity exercise increases PER1 in mice (p = 0.031).
“Per1 gene, for which expression was increased (p = 0.031) by low-intensity exercise”
Animalsheart
Clock Gene Expression Modulation by Low- and High-Intensity Exercise Regimens in Aging Mice
International journal of molecular sciences8 Sep 2025