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Liuweirunfu oil

Intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: Science and Technology Commission of Shanghai Municipality and 2 more
  • Human trial1

Outcomes

4

Immune response

downin mice1

1 study

  1. Liuweirunfu oil inhibits immune response in mice.

    “Furthermore, LWRF Oil modulated Th2 cell responses, dampening their infiltration and activation in the skin.”

    Animalsskin

    Reversal of BCAA-driven inflammatory senescence by traditional herbal oil prevents atopic dermatitis relapse

    Phytomedicine : international journal of phytotherapy and phytopharmacology20 Oct 2025

More on Immune response

CDKN1A

downin mice1

1 study

  1. Liuweirunfu oil decreases CDKN1A in mice.

    “leading to reduced expression of the senescence marker P21.”

    Animalsskin

    Reversal of BCAA-driven inflammatory senescence by traditional herbal oil prevents atopic dermatitis relapse

    Phytomedicine : international journal of phytotherapy and phytopharmacology20 Oct 2025

More on CDKN1A

Cellular senescence

downin mice1

1 study

  1. Liuweirunfu oil inhibits cellular senescence in mice.

    “LWRF Oil reversed inflammatory senescence in a murine AD model by selectively enhancing BCAT1-mediated BCAA catabolism, leading to reduced expression of the senescence marker P21.”

    Animalsskin

    Reversal of BCAA-driven inflammatory senescence by traditional herbal oil prevents atopic dermatitis relapse

    Phytomedicine : international journal of phytotherapy and phytopharmacology20 Oct 2025

More on Cellular senescence

Atopic dermatitis relapse

downin humans1

1 study

  1. Liuweirunfu oil decreases atopic dermatitis relapse in humans.

    “topical LWRF Oil significantly reduced relapse rates and improved clinical outcomes in AD patients during remission”

    Human trialduring remission

    Reversal of BCAA-driven inflammatory senescence by traditional herbal oil prevents atopic dermatitis relapse

    Phytomedicine : international journal of phytotherapy and phytopharmacology20 Oct 2025

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